Antioxidant and antibacterial activities of Hibiscus Rosa-sinensis Linn flower extracts

Antioxidant and antibacterial potential of different solvent extracts of locally grown Hibiscus rosa-sinensis Linn was evaluated. The antioxidant activity was assessed by estimation of total flavonoids contents, total phenolic contents, DPPH free radical scavenging activity and percentage inhibition of linoleic acid oxidation capacity. Agar disc diffusion method was used to assess antibacterial potential of crude extract of H. rosa-sinensis. The yield of the crude extracts [23.21 +/- 3.67 and 18.36 +/- 2.98% in 80% methanol and ethanol solvents was calculated, respectively. Methanol and ethanol extract of H. rosa-sinensis showed total phenolics 61.45 +/- 3.23 and 59.31 +/- 4.31 mg/100g as gallic acid equivalent, total flavonoids 53.28 +/- 1.93 and 32.25 +/- 1.21 mg/100g as catechine equivalent, DPPH free radical scavenging activity 75.46 +/- 4.67 and 64.98 +/- 2.11% and inhibition of linoleic acid oxidation potential 75.8 +/- 3.22 and 61.6 +/- 2.01% respectively, was measured. Antibacterial study against three human pathogens such as staphlococus sp. Bacillus sp. and Escherichia coli showed growth inhibitory effect in the range of 12.75 +/- 1.17 to 16.75 +/- 2.10 mm. These results showed H. rosasinensis indigenous to Kallar Kahar and its allied areas bear promising medicinal values and could be used for developing herbal medicines to target oxidative stress and infectious diseases.

Adenocystic carcinoma of eyelid: a case report and review of literature

Adenoid cystic carcinoma [ACC] is a rare slow growing epithelial malignancy. ACC is an intractable neoplasm due to its ability to invade perineural spaces. In eye, ACC most commonly arises in the lacrimal gland. Very rarely, ACC originates from accessory lacrimal gland tissue. In the rare instance of taking origin from eyelid, it can arise from eyelid skin, glands of Moll, palpebral lobe of lacrimal gland, accessory lacrimal glands in conjunctiva, or from ectopic lacrimal gland tissue. Here, we present a patient with an ACC of the outer part of upper eyelid, clinically presenting like sebaceous gland carcinoma. Its origin most likely was palpebral lobe of lacrimal gland. Palpebral lobe tumors should be strongly considered in the differential diagnosis of upper outer eyelid masses